Dheer Healthcare Private Limited

Dextrose and Sodium Chloride Injections USP are sterile, nonpyrogenic and contain no bacteriostatic or antimicrobial agents. These products are intended for intravenous administration.

Indications and Usage for Dextrose and Sodium Chloride Injection

• These intravenous solutions are indicated for use in adults and pediatric patients as sources of electrolytes, calories and water for hydration.

Contraindications:

• These solutions are contraindicated where the administration of sodium or chloride could be clinically detrimental.
• Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products.

• The administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentration. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentration.

• Clinical studies of Dextrose and Sodium Chloride Injections USP did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between elderly and younger patients.

• In the event of a fluid or solute overload during parenteral therapy, reevaluate the patient''s condition and institute appropriate corrective treatment.

• Hydrocortisone is a natural substance (Corticosteroid hormone) made by the adrenal gland. It is used to treat conditions such as arthritis, blood/hormone/immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system''s response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions. Hydrocortisone is also used to treat low hydrocortisone levels caused by diseases of the adrenal gland (such as addison''s disease, adrenocortical insufficiency). Corticosteroids are needed in many ways for the body to function well. They are important for salt and water balance and keeping blood pressure normal.

• Nausea, heartburn, headache, dizziness, menstrual period changes, trouble sleeping, increased sweating, or acne may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Because this drug works by weakening the immune system, it may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as cough, sore throat, fever, chills). Use of this medication for prolonged or repeated periods may result in oral thrush or a yeast infection. Contact your doctor if you notice white patches in your mouth or a change in vaginal discharge. This medication may rarely make your blood sugar level rise, which can cause or worsen diabetes. Tell your doctor right away if you develop symptoms of high blood sugar such as increased thirst and urination. If you already have diabetes, be sure to check your blood sugars regularly. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

• Before taking hydrocortisone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye disease (such as cataracts, glaucoma), heart problems (such as heart failure, recent heart attack), high blood pressure, liver disease, kidney disease, thyroid problems, diabetes, stomach/intestinal problems (such as diverticulitis, ulcer), brittle bones (osteoporosis), current/past infections (such as tuberculosis, positive tuberculosis test, herpes, fungal), bleeding problems, blood clots, mental/mood conditions (such as psychosis, anxiety, depression), low salts in the blood (such as low potassium or calcium), seizures. This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

• This solution is used to supply water and salt (sodium chloride) to the body. Sodium chloride solution may also be mixed with other medications given by injection into a vein.
• How to use Sodium Chloride Solution, Intravenous
• This solution is usually given by injection into a vein as directed by your doctor. It may be given in the hospital, in a clinic, or at home.
• If you are using this product at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If you are mixing this solution with another medication, ask your doctor or pharmacist if it is proper to mix it with the medication. Learn how to store and discard medical supplies safely.
• The dosage is based on your age, weight, medical condition, and response to treatment.

• Redness, pain, or swelling at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
• Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication donot have serious side effects.

• Before using this product, tell your doctor or pharmacist if you have any allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this product, tell your doctor or pharmacist your medical history, especially of: kidney problems, heart problems (such as heart failure), body water/salt imbalance.

• Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor''s approval.

• Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacistor local waste disposal company.Information last revised July 2016. Copyright(c) 2016 First Databank, Inc.

• Manufactured by bharat serum, is an infusion of horse or rabbit-derived antibodies against human t cells, which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia. Thymogam is a sterile, transparent to slightly opalescent aqueous colourless to pale yellow solution containing antithymocyte globulin.

• Applies to anti-thymocyte globulin (rabbit): intravenous powder for solution. As well as its needed effects, anti-thymocyte globulin (rabbit) may cause unwanted side effects that require medical attention. Because of the way that anti-thymocyte globulin (rabbit) acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas and skin cancers. Discuss these possible effects with your doctor. Although not all of these side effects may occur, if they do occur they may need medical attention.

• Moderate If any of the following side effects occur while taking anti-thymocyte globulin (rabbit), check with your doctor or nurse as soon as possible:

• Black, tarry stools Bladder pain Chest pain Chills Cloudy or bloody urine Cold Confusion Cough or hoarseness Fast heartbeat Fever Flu-like symptoms Frequent urge to urinate High blood pressure Irregular or slow heartbeat Lower back or side pain Numbness or tingling around lips hands, or feet Painful or difficult urination Shortness of breath or troubled breathing Sore throat Sores, ulcers, or white spots on lips or in mouth Swollen glands Tiredness or weakness Unexplained anxiety Unusual bleeding or bruising Weakness or heaviness of legs Less common:Burning or stinging of skin Painful cold sores or blisters on lips, nose, eyes, or genitals Minor side effects Some anti-thymocyte globulin (rabbit) side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

• Abdominal pain Diarrhea Difficult or labored breathing Dizziness General feeling of discomfort or illness Headache Loss of strength or energy Muscle pain or weakness Nausea Pain Swelling of ankles, feet, and fingers Tightness in chest Unusual weak feeling Wheezing Less common:White patches on mouth, tongue, or throat

• Fluticasone belongs to a class of drugs called glucocorticoids/steroids. It prevents the release of the substances in the body that cause inflammation and allergies.Common side effects : Electrolyte imbalance, Headache, Redistribution/accumulation of body fat, Bone degradation, Chest tightness, Hoarseness of voice, Increased risk of infection, Nasal congestion, Muscle disorders, Vomiting, White spots in the mouth, Nausea, Sneezing, Sore throat, Fever, Sinus pain, Increased blood pressure, Cough, Altered bone growth, Skin scar, Nose bleed, Stomach upset, Behavioural changes, Increased glucose level in blood, Cataract

• Interaction with alcohol is unknown.
• Please consult your doctor.

• Seretide 250 evohaler may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Unknown. Human and animal studies are not available. Please consult your doctor.

• Acute adrenal insufficiency.
• Chronic adrenal insufficiency (addisons disease).
• Congenital adrenal hyperplasia (adrenogenital syndrome).

• Fludrocortisone acetate

• This medication is used to treat certain types of arthritis (rheumatoid arthritis, arthritis of the spine, psoriatic arthritis), certain bowel diseases (crohn''s disease, ulcerative colitis), and a certain severe skin disease (chronic plaque psoriasis). In these conditions, the body''s defense system (immune system) attacks healthy tissues. Infliximab works by blocking the actions of a certain natural substance (tumor necrosis factor alpha) in the body. This helps to decrease swelling (inflammation) and weaken your immune system, thereby slowing or stopping the damage from the disease.

Additional Information:

• Delivery Time: 7 DAYS
• Packaging Details: 28 TABLET

Additional Information:

• Delivery Time: as per requirement

Additional Information:

Item Code: 117772-70-0

• Burning, dry, or itching eyes chest pain chills cough difficult breathing discharge or excessive tearing dry eyes general feeling of discomfort or illness redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid thickening of bronchial secretions troubled breathing troubled or quick, shallow breathing

• Blistering, peeling, or loosening of the skin bloody, black, or tarry stools eye redness, irritation, or pain heart burn indigestion joint or muscle pain red skin lesions, often with a purple center severe abdominal or stomach pain, cramping, or burning sore throat sores, ulcers, or white spots in the mouth or on the lips vomiting of material that looks like coffee grounds, severe and continuing

• Some of the side effects that can occur with gefitinib may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

• Redness or soreness around fingernails or loosening of the fingernails.

• Phenytoin is a hydantoin in derivative.

Mechanism of action:

The mechanism by which phenytoin accelerates wound healing is unknown. Clinical, animal and in vitro studies suggest that phenytoin may be involved in the healing process at several levels including stimulating fibroblast proliferation, enhancing the formation of granulation tissue, decreasing collagenase activity (by reducing its production for secretion or both), promoting deposition of collagen and other connective tissue components, decreasing bacterial contamination, and decreasing wound exudates. Biopsies of phenytoin treated open wounds show neovascularization, collagenization and decreased polymorphonuclear and eosinophil cell infiltration. A number of clinical studies indicate that phenytoin decreases the bacterial load of wounds. Topical phenytoin was reported to eliminate Staphylococcus aureus, E. coil, Klebsiella spp. And Pseudomonas spp. from wounds within 7-9 days. Phenytoin more readily cleared gram negative organisms than gram positive bacteria form wounds.

Local pain relief has also been observed with topical phenytoin therapy , which topical phenytoin therapy , which can be explained by its membrane stabilizing action; the reduced inflammatory response may also contribute. Facilitation of nerve regeneration has also been reported with phenytoin .

Indications:

Topical phenytoin has proven useful for a wide variety of soft tissue wounds. Some of these include leprosy trophic ulcers, decubitus ulcers, diabetic foot ulcers, burns, traumatic wounds, venous stasis ulcers and abscesses. Topical phenytoin also appears to be potentially useful in epidermolysis bullosa simplex.

Contraindications:

• Hypersensitivity to the active substance or other hydantoins or to any of the excipients used in the formulation.

Side Effects:

• Side effect from topical phenytoin are rare. Some patients have a transient burning sensation when the cream is initially applied. A generalized rash that resolved when treatment was stopped has also been reposted .

Additional Information:

• Pay Mode Terms: T/T (Bank Transfer)

5% Dextrose Injection, USP solution is sterile and nonpyrogenic. It is a parenteral solution containing dextrose in water for injection intended for intravenous administration.

Each 100 mL of 5% Dextrose Injection, USP, contains dextrose monohydrate, 5 g in water for injection. The caloric value is 170 kcal/L. The osmolarity is 252 mOsmol/L (calc.), which is slightly hypotonic.

his solution contains no bacteriostat, antimicrobial agent or added buffer and is intended only as a single-dose injection. When smaller doses are required the unused portion should be discarded.

5% Dextrose Injection, USP is a parenteral fluid and nutrient replenisher.

Dextrose, USP is chemically designated D-glucose monohydrate (C6H12O6 • H2O), a hexose sugar freely soluble in water. It has the following structural formula:

Water for Injection, USP is chemically designated H2O.

The flexible container is fabricated from a specially formulated non-plasticized film containing polypropylene and thermoplastic elastomers (freeflex® bag). The amount of water that can permeate from the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the flexible container can leach out certain of the container’s chemical components in very small amounts within the expiration period. The suitability of the container material has been confirmed by tests in animals according to USP biological tests for plastic containers.

• When administered intravenously, these solutions provide a source of water and carbohydrate.
• Isotonic and hypertonic concentrations of dextrose are suitable for parenteral maintenance of water requirements when salt is not needed or should be avoided.

• Intravenous solutions containing dextrose are indicated for parenteral replenishment of fluid and minimal carbohydrate calories as required by the clinical condition of the patient.

• 5% Dextrose Injection, USP without electrolytes should not be administered simultaneously with blood through the same infusion set because of the possibility that pseudoagglutination of red cells may occur.

• Excessive administration of potassium-free solutions may result in significant hypokalemia.The intravenous administration of these solutions can cause fluid an

Preparations:

• Tablets (immediate release): 250, 500, 750 and 1000 mg. Tablets (extended release): 500 and 750 mg. Oral solution: 100 mg/ml. Injection solution: 5, 10, 15, and 100 mg/ml.

Storage:

• Levetiracetam should be stored at 25 C (77 F). Brief storage at 15 C to 30 C (59 F to 86 F) is acceptable.

Prescribed For:

• Levetiracetam is used in combination with other anti-seizure medications to treat myoclonic, partial onset, or tonic clonic seizures in children and adults.

Dosing:

• The recommended daily dose of levetiracetam in adults is 3000 mg. Therapy is initiated with 1000 mg daily (500 mg twice daily) and increased by 1000 mg/day every two weeks up to the maximum recommended dose of 3000 mg/day.
• Immediate release tablets, oral solution, and intravenous solutions are administered twice daily, and extended release tablets are administered once daily.
• The recommended daily dose for children is 60 mg/kg (30 mg/kg twice daily). Therapy is initiated with 20 mg/kg (10 mg/kg twice daily) and increased by 20 mg/kg every two weeks until the recommended daily dose of 60 mg/kg is reached.

• You should check with your doctor immediately if any of these side effects occur when taking darbepoetin alfa:

• Abdominal or stomach pain Accumulation of pusArm, back, or jaw pain Blurred vision Breathing problems (irregular, noisy, or trouble when resting)Chest pain, discomfort, tightness, or heaviness Chills Confusion Cough producing mucus Decrease in the amount of urine Diarrhea Dilated neck veins Dizziness, fainting, or light headedness Dry mouth Fast, slow, or irregular heart beat Fatigue or tiredness (extreme or unusual)Fever Headache Nausea Pain, tenderness, swelling, or warmth over injection site Pounding in the ears Rapid breathing Rapid or pounding pulse Shortness of breath Skin discoloration at the injection site Sunken eyes Sweating Swelling of the ankles, face, fingers, feet, hands, or lower legs Thirst Trouble with breathing Unconsciousness Vomiting Weight gain Wheezing Wrinkled skin
  

• Distinon bromide is an orally active cholinesterase inhibitor. Distinon bromide is useful in the treatment of myasthenia gravis. 

• Pyridostigmine

• Elidel (pimecrolimus) is an immunosuppressant. It works by decreasing your body's immune system to help slow down the growth of atopic dermatitis (eczema) on your skin.Elidel cream is used to treat severe atopic dermatitis (eczema} when other medications have not worked well. Elidel cream may also be used for purposes not listed in this medication guide.

• You should not use elidel if you are allergic to pimecrolimus, or if you have a bacterial or viral skin infection (including herpes or chicken pox).To make sure elidel is safe for you, tell your doctor if you have any of these conditions:Skin cancer or any type of skin infection;Netherton's syndrome (a genetic skin disorder);A weak immune system (caused by disease or by using certain medicines); orSwelling, redness, or irritation over large skin areas.

• You should check with your doctor immediately if any of these side effects occur when taking pimecrolimus topical:

• Abdominal or stomach painBody aches or painBurning, itching, redness, skin rash, swelling, or soreness at the application siteChange in hearingChillsCold or flu-like symptomsCongestion (ear or nasal)Cough producing mucusDiarrheaDifficulty with breathing or shortness of breathDryness or soreness of the throatEarache or pain in the earEar drainageFeverGeneral feeling of discomfort or illnessHeadacheHoarsenessItchingJoint painLoss of appetiteLoss of voiceMuscle aches and painsNauseaPainRednessRunny.

• Some of the side effects that can occur with pimecrolimus topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

• Burning, itching, and pain in hairy areasPus at the root of the hair

• Blemishes on the skinBloody noseBurning or stinging of the skinDifficulty having a bowel movement (stool)Flushing; redness of skin; unusually warm skin at siteHeavy bleedingPainful cold sores or blisters on the lips, nose, eyes, or genitalsPimplesRedness or swelling in the earVaginal pain and cramps

• Burning, stinging, itching, or mild discomfort of the eye (after applying the cream to the eyelids or near the eyes)Feeling of warmth (with alcohol use)Redness of the face, neck, arms, and occasionally, upper chest (with alcohol use).

• Frequent urge to urinate, abdominal pain, anxiety, excitement, flushing, altered heart rate, insomnia, restlessness, tremor.How it

• Apnicaf injection is a drug which belongs to a group of medicines called methylxanthines. Apnicaf injection acts against a chemical called adenosine in the body, and thereby reduces pain. Apnicaf injection also stimulates the brain (central nervous system), heart, and muscles and improves the drive to breathe.

• Adrenor 4mg injection is used in the treatment of decreased blood pressureHow adrenor injection worksNACommon side effects of adrenor injection :Systemic hypertension (high blood pressure), Headache, Restless, Insomnia (difficulty in sleeping), Palpitations, Tremor

• Interaction with alcohol is unknown.
• Please consult your doctor.

• Adrenor 4mg injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Adrenor 4mg injection is probably safe to use during breastfeeding. Please consult your doctor.

• Renodapt- 500 (Mycophenoiate Mofetil Tablets) is the 2-morpholinoethyl ester of mycophenolic acid (Mycophenolic Acid), an immunosuppressive agent; inosine monophosphate dehydrogenase (IMPDH) inhibitor used to prevent rejection in allogenic organ transplant.

• Renodapt- 500
• Each film coated tablet contains:
• Mycophenolate Mofetil IP 500mg
• Excipients q.s.

Additional Information:

• Item Code: 10104

• Capegard is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capegard is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of Capegard follows a pathway with three enzymatic steps and two intermediary metabolites, 5''-deoxy-5-fluorocytidine (5''-DFCR) and 5''-deoxy-5-fluorouridine (5''-DFUR), to form 5-fluorouracil.

• It is used alone or in combination in the adjuvant and palliative treatment of gastrointestinal cancer and breast cancer.

Molecular Formula: C25H31NO6

Molecular Weight: 441.52

CAS: 14484-47-0

Function and usage:

Deflazacort is derived from prednisolone, a systemic corticosteroids.

Appearance: white or almost white powder 

Solubility test Freely soluble in acetic acid, methylene chloride, slightly

soluble in ethanol, acetone,

methanol, insoluble in water 

Assay 97.0%~102.0%

SPECIFICATION Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant. Deflazacort is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort. Its potency is around 70–90% that of prednisone.

Storage Store in a well-closed container away from moisture

Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.14,Label

Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which is important for muscle function. This disease can cause serious muscle weakness and progressive breathing and cardiovascular disability, severely impacting patient quality of life and survival.3,4,15 This disease usually manifests by muscle weakness in early childhood followed by loss of the ability to walk (ambulation) as early as age 7.4

Deflazacort delays the onset of muscle related complications resulting from DMD6, prolonging the lives of children diagnosed with this disease and exerting less harmful effects on the bone health and weight than other steroid medications.

Additional Information:

Item Code: 14484-47-0

• Interaction with alcohol is unknown. Please consult your doctor.

• Adrenaline tartrate injection may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Adrenaline tartrate injection is probably safe to use during breastfeeding. Please consult your doctor.

• In combination with other antiretroviral agents for the treatment of HIV-1 infection.

• Treatment of HIV infection in combination with zidovudine.
• Chronic Hepatitis B.

• Lamivudine/Nevirapine/Stavudine